Among the companies with shares expected to trade actively in Wednesday's session are Sarepta Therapeutics Inc., Hewlett Packard Enterprise Co., and Computer Sciences Corp.
Sarepta Therapeutics said the U.S. Food & Drug Administration would work beyond Thursday's deadline to review its muscular dystrophy drug that an advisory panel last month recommended the agency reject. The company's shares shot up 21% to $22.25 in premarket trading.
Hewlett Packard plans to spin off most of its technology services operations and merge them with those of Computer Sciences Corp., the company's latest adjustment to a shifting landscape that is roiling the market for corporate technology. Under the proposed deal, HP Enterprise would shed a business that accounts about 100,000 employees, or about two-thirds of the Silicon Valley giant's workforce. Shares of Hewlett Packard rose 12% to $18.13 premarket, while shares of Computer Sciences jumped 31% to $46.74.
Express Inc. slashed its guidance for the year and gave a bleak outlook for the current quarter, as the apparel chain reported disappointing sales growth in the most recent quarter amid a tough retail environment. Shares of Express dropped 15% to $13.56 premarket.
Tiffany & Co. said its sales fell more than Wall Street anticipated in the latest quarter, again hurt by lower tourist spending, and warned that earnings for the current period will be worse than it previously feared. The company's shares slipped 3.6% to $61.70 premarket.
French drugmaker Sanofi SA said Wednesday it is moving to call a vote on whether to remove the entire board of Medivation Inc. after the U.S. biotech company refused to engage in takeover talks.
Microsoft Corp., struggling to restart its mobile strategy after multiple misfires, early on Wednesday announced a further step in dismantling the mobile-phone operations it acquired from Nokia Corp.
Gilead Sciences Inc. on Tuesday named Kevin Young as its chief operating officer, an appointment that puts him in charge of responsibilities vacated by departing head of commercial operations, Paul Carter.
Shares of specialty contracting services company Dycom Industries Inc. rose on much better-than-expected fiscal third-quarter earnings and revenue.
Intuit Inc., the maker of TurboTax software, on Tuesday raised its earnings guidance for the year as it reported strong third-quarter results bolstered by the sale of several businesses.
Exelon Corp., which has threatened to close two nuclear power plants in Illinois if lawmakers don't provide support, said one of the plants failed to secure contracts after a recent round of bidding.
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